gsk-3 inhibitor 3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T77342	GSK-3 inhibitor 3		GSK-3 , Microtubule Associated
	GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and GSK-3β with IC50s of 0.35 nM and 0.25 nM, respectively.GSK-3 inhibitor 3 reduces the phosphorylation level of tau ...		GSK-3 , Microtubule Associated
T35554	GSK-3β inhibitor 3		Apoptosis , GSK-3
	GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3 can be used to study acute promyelocytic leukemia.		Apoptosis , GSK-3
T11468	GSK-3 inhibitor 1		GSK-3
	GSK-3 inhibitor 1 is a GSK-3 inhibitor.		GSK-3
T1917	GSK 3 Inhibitor IX	BIO,GSK 3 IX,6-BIO,6-Bromoindirubin-3'-oxime,MLS 2052,6-bromoindirubin-3-oxime	Apoptosis , GSK-3 , Tyrosine Kinases , CDK
	GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex. It inhibits (GSK-3α/β)/CDK1/CDK5 activity with IC50 values of 5 nM/320 nM/83 nM, respectively.		Apoptosis , GSK-3 , Tyrosine Kinases , CDK
T77554	GSK-3 Inhibitor 5	4-Cyanophenacyl bromide	GSK-3
	GSK-3 Inhibitor 5 (4-Cyanophenacyl bromide) is a ketone derivative that is used as an intermediate in pharmaceuticals and organic synthesis, and inhibits glycogen synthase kinase 3 (GSK-3).		GSK-3
T77341	GSK-3 inhibitor 4		GSK-3 , CDK
	GSK-3 inhibitor 4 is an orally active and brain-permeable triple inhibitor of GSK-3, CDK2 and CDK5 with inhibitory effects on GSK-3β, GSK-3α, CDK2 and CDK5, with IC50 values of 0.56 nM, 0.45 nM, 0.47 μM, 0.68 μM, respect...		GSK-3 , CDK
T11467	GSK-3β inhibitor 1		GSK-3
	GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.		GSK-3
T6787	BIO-acetoxime	BIA,GSK-3 Inhibitor X	Apoptosis , GSK-3 , HSV
	BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.		Apoptosis , GSK-3 , HSV
T9725	GSK-3β inhibitor 10		Others
	GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities.		Others
T78578	GSK-3 Inhibitor XIII		GSK-3
	GSK-3 Inhibitor XIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.		GSK-3
T9178	(E/Z)-GSK-3β inhibitor 1	GSK-3β inhibitor 1	GSK-3
	(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.		GSK-3
T24111	GSK3i XIII	GSK3 inhibitor XIII,GSK3iXIII,GSK3i-XIII	GSK-3
	GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.		GSK-3
T2073	GSK2636771	GSK 2636771,GSK-2636771	PI3K
	GSK2636771, an effective, specific, orally bioavailable, PI3Kβ inhibitor, has been used in cancer, lymphoma, solid neoplasm, recurrent solid neoplasm, and advanced malignant neoplasm.		PI3K
T6187	TDZD-8	GSK-3β Inhibitor I,NP 01139	GSK-3
	TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.		GSK-3
T1965	Bikinin	Abrasin	Others , GSK-3
	Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.		Others , GSK-3
T1881	AR-A014418	AR 0133418,GSK-3beta Inhibitor VIII,AR 014418,GSK 3β inhibitor VIII	GSK-3
	AR-A014418 (GSK 3β inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor.		GSK-3
T9987	GSK3-IN-1		GSK-3
	GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.		GSK-3
T10202	A 1070722		GSK-3
	A 1070722 is a potent and selective GSK-3 inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β. It can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for...		GSK-3
T2357	GSK1059615	GSK 1059615,GSK-1059615	Apoptosis , PI3K , mTOR
	GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.		Apoptosis , PI3K , mTOR
T1741	AZD1080		GSK-3
	AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.		GSK-3